---
id: CVE-2026-100845
title: >-
  MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the
  NumpyReader class that unconditionally uses numpy.load with allow_pickle=True
  when loading .npy and .npz files
summary: >-
  MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the
  NumpyReader class that unconditionally uses numpy.load with allow_pickle=True
  when loading .npy and .npz files. Attackers can craft malicious .npy files
  with pick…
severity: high
cvss: 7.8
cvssVector: 'CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H'
cwe:
  - CWE-502
vendor: Project-MONAI
product: MONAI
affected:
  - MONAI < 1.6.0
published: '2026-09-27'
updated: '2026-09-27'
sourceUpdated: '2026-09-27T02:17:23.140'
source: NVD
sourceUrl: 'https://nvd.nist.gov/vuln/detail/CVE-2026-100845'
references:
  - url: >-
      https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-wg9g-w2j2-8pgr
    label: disclosure@vulncheck.com
  - url: >-
      https://www.vulncheck.com/advisories/monai-before-1.6.0-remote-code-execution-via-numpyreader
    label: disclosure@vulncheck.com
tags:
  - nvd
  - cve.org
ingestedAt: '2026-09-27T02:41:45.574Z'
---

## Overview

MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.

## Remediation

Refer to the linked advisories for vendor-supplied fixes and affected version ranges.