---
id: CVE-2025-12921
title: >-
  A vulnerability has been found in OpenClinica Community Edition up to
  3.12.2/3.13
summary: >-
  A vulnerability has been found in OpenClinica Community Edition up to
  3.12.2/3.13. Affected by this issue is some unknown functionality of the file
  /ImportCRFData?action=confirm of the component CRF Data Import. Such
  manipulation of the …
severity: medium
cvss: 4.3
cvssVector: 'CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N'
cwe:
  - CWE-74
  - CWE-91
  - CWE-91
vendor: openclinica
product: openclinica
affected:
  - openclinica = 3.12.2
  - openclinica = 3.13
published: '2025-11-10'
updated: '2026-10-07'
sourceUpdated: '2026-10-07T21:10:00.200'
source: NVD
sourceUrl: 'https://nvd.nist.gov/vuln/detail/CVE-2025-12921'
references:
  - url: >-
      https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md
    label: cna@vuldb.com
  - url: >-
      https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc
    label: cna@vuldb.com
  - url: 'https://vuldb.com/?ctiid.331641'
    label: cna@vuldb.com
  - url: 'https://vuldb.com/?id.331641'
    label: cna@vuldb.com
  - url: 'https://vuldb.com/?submit.680872'
    label: cna@vuldb.com
  - url: >-
      https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md
    label: 134c704f-9b21-4f2e-91b3-4a467353bcc0
  - url: >-
      https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc
    label: 134c704f-9b21-4f2e-91b3-4a467353bcc0
tags:
  - nvd
epss: 0.00529
epssPercentile: 0.42934
ingestedAt: '2026-10-07T21:54:14.996Z'
---

## Overview

A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.

## Affected

- `openclinica = 3.12.2`
- `openclinica = 3.13`

## Remediation

Refer to the linked advisories for vendor-supplied fixes and affected version ranges.