{"id":"CVE-2026-100845","title":"MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files","summary":"MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pick…","severity":"high","cvss":7.8,"cvssVector":"CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H","cwe":["CWE-502"],"vendor":"Project-MONAI","product":"MONAI","affected":["MONAI < 1.6.0"],"published":"2026-09-27","updated":"2026-09-27","sourceUpdated":"2026-09-27T02:17:23.140","source":"NVD","sourceUrl":"https://nvd.nist.gov/vuln/detail/CVE-2026-100845","references":[{"url":"https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-wg9g-w2j2-8pgr","label":"disclosure@vulncheck.com"},{"url":"https://www.vulncheck.com/advisories/monai-before-1.6.0-remote-code-execution-via-numpyreader","label":"disclosure@vulncheck.com"}],"tags":["nvd","cve.org"],"ingestedAt":"2026-09-27T02:41:45.574Z","slug":"CVE-2026-100845","body":"## Overview\n\nMONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.\n\n## Remediation\n\nRefer to the linked advisories for vendor-supplied fixes and affected version ranges.","depth":"twilight","depthScore":43,"depthScoreParts":{"impact":42.9,"likelihood":0,"exploitation":0,"ransomware":0},"changes":[]}